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Prescription Drug Abuse

Abuse of Over-the-Counter Drugs

Over-the-counter cold and cough medicines containing the drug dextromethorphan (DXM) are also commonly abused. DXM comes in syrups, gels and tablets. Powdered DXM sold online poses a high risk because the potency is uncertain. It is found in over 100 cough and cold products, Coricidin, Delsym and Robitussin being the most abused.

Brand Names

  • Comtrex
  • Coricidin
  • Delsym
  • Dimetapp
  • Mucinex DM
  • Robitussin
  • Triaminic
  • Vicks Formula 44

Street Names

  • CCC
  • DXM
  • Poor Man’s PCP
  • Robo
  • Skittles
  • Triple C

Cough Syrup (DXM) Effects

  • Hallucinations
  • Hyperexcitability
  • Insomnia
  • Lethargy
  • Physical dependence (with prolonged use)
  • Paranoia
  • Dizziness
  • Slurred speech
  • Delusions
  • Sweating
  • High blood pressure
  • Liver and brain damage

Mixed with other drugs or by itself, DXM depresses the action of the brain and nervous system, which can interfere with breathing and the functioning of the heart. Large doses can cause a loss of consciousness, seizures, brain damage or death. DXM is particularly dangerous when combined with alcohol.

My experience with DXM: I started peeing blood. I felt sick. My body felt weak. I gave up everything because I was obsessed with using. All I cared about was getting high. I thought I could just use Coricidin for fun, that it didn’t matter. I never expected to get hooked. I’ll never be able to get that time back. If I could erase it and make it go away, I would.” —Crystal

How much do you really know about prescription drug abuse?

Updated: 2025