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Synthetic Drugs

Synthetic Marijuana Short-Term Effects

Effects on the Mind:

  • Unresponsiveness
  • Loss of consciousness
  • Confusion
  • Altered time sense
  • Extreme anxiety
  • Panic attacks
  • Severe paranoia
  • Delusions
  • Hallucinations
  • Psychosis
  • Potential suicide

Effects on the Body:

  • Nausea and vomiting
  • Heavy sweating
  • Uncontrolled or spastic body movements
  • Acute kidney injury
  • Rapid heart rate
  • High blood pressure
  • Reduced blood supply to the heart
  • Heart attack
  • Convulsions
  • Seizures
  • Stroke

Synthetic Marijuana Long-Term Effects

The long-term effects on humans are not fully known, but poison center experts report that the effects of synthetic marijuana can be life-threatening.

It can be addictive and cause withdrawal symptoms, including cravings, nightmares, heavy sweating, nausea, tremors, headaches, extreme tiredness, insomnia, diarrhea, vomiting, difficulties thinking clearly and neglect of other interests or responsibilities.

With repeated and long-term use of the drug, users may experience forgetfulness and confusion. Some users have even reported paralysis.

This Is What Hell Is

“I want to share my experience with K2. It ruined my life. When I tried smoking K2 for the first time, it was like everything dissolved into what seemed like the fuzz on the TV screen. I remember thinking, ‘This is what hell is.’ All I could feel was awful fear. I heard voices of family members, flashbacks to when I was younger—it was the worst experience I’ve ever had. I was shaking horribly, and I felt terrified and sick. Ever since that day, I have had awful anxiety on a daily basis. I had to quit school because my anxiety was so bad.” —J.W.

Paralyzed after Smoking Spice

“After using Spice for several weeks, I woke up early one night, fell to the floor, couldn’t move my legs and couldn’t move my hips. All I could do was drag myself by my forearms. I laid on the floor for 13 hours screaming, pounding the floor, asking for help. Doctors say another two hours and I would have been dead. I’m going to be in the hospital for a long time to come.” —L.D.

I Am Just Not All There Anymore

“I overdosed on Spice and I haven’t been the same since. I was just sitting there smoking until it all hit me. I couldn’t see straight or walk, and then I threw up about six or seven times. I woke my mom up, and she laid me down on the couch and called an ambulance. About 10 minutes before the ambulance showed up, I started to have seizures. I woke up in a hospital bed on life support. I had gone into cardiac arrest* for a few hours, and they thought I wasn’t going to wake up. I survived it, but I have not been the same. I stutter a lot now and I can’t concentrate on anything. I’ll be telling a story and just go blank and not know what happened. I always see these dots, and I am just not all there anymore.” —D.Y.

A Former Addict

“I am a former Spice addict. I became hooked while on probation. I went from a gram or less a day to over three or four a day. As my addiction progressed, my motor skills and ability to control basic behaviors deteriorated. I grew more aggressive when I got upset, which became more frequent the more and longer I used. One morning I had a psychotic break, during which I blacked out and almost killed my wife. I was arrested, and my probation was revoked. Since being released, I share my experience with others to encourage them not to use this drug.” —S.W.

* cardiac arrest: a sudden, sometimes temporary, stopping of the heart

Violent and Irrational Behavior

A 21-year-old mother under the influence of Spice threw her four-year-old child into a trash bin. When the police arrested her, she could not remember where her son was. The child was later found in the trash by the police and handed over to Child Protective Services. The woman was charged with abandoning her child.

A US teen shot two school administrators, killing one, before taking his own life. Medical tests found K2 in his system.

A 21-year-old man slit his throat while using K2 for the first time. Thankfully, his mother was able to control the bleeding until help arrived.

How much do you really know about synthetic drugs?

Updated: 2025